I treat setbacks as a lesson learned on what I should not do the next time. This applies to financial loss or a lost love or a failed deal.
I'd rather die than give up on my dreams. I look at every day I get to live as a gift to keep on striving towards what I want to accomplish. I owe it to myself, my family and everyone who ever gave me a chance. So as Norman Cousins said "The tragedy of life is not death, but what we let die inside us while we live."